Bone Metastasis: Current State of Play

Current state of bone scintigraphy protocols and practice in Japan

Objective(s): Nuclear medicine technologists in Japan often perform additional single-photon emission computed tomography (SPECT) with or without computed tomography (CT) after whole-body imaging for bone scintigraphy. In this study, we wanted to identify the bone scanning protocols used in Japan, together with the current clinical practices. Methods:...

Inflammometry: the current state of play.

It is now 20 years since the late Freddy Hargreave and colleagues developed a valid, safe and feasible technique to assess airway inflammation using induced sputum. At around the same time Kjell Alving and colleagues reported that the concentration of exhaled nitric oxide (FENO) is raised in patients with asthma. There has since been huge research interest in these techniques over the last 20 y...

Report on the current state of play

Diagnostic and Prognostic Biomarkers in Melanoma: Current State of Play

Melanoma is the most deadly skin cancer. The incidence and mortality rates of this tumor have been increasing over the last number of decades. Besides clinical and histopathological characteristics (i.e., anatomic site and subtype of the primary tumor, Breslow thickness, ulceration, vascular invasion, mitotic index), an increasing variety of molecular markers have been identifi ed, providing th...

Working Memory and Consciousness: The Current State of Play

Working memory (WM), an important posit in cognitive science, allows one to temporarily store and manipulate information in the service of ongoing tasks. WM has been traditionally classified as an explicit memory system-that is, as operating on and maintaining only consciously perceived information. Recently, however, several studies have questioned this assumption, purporting to provide eviden...